Tufts Discovery Pathology is dedicated to helping industry and academic clients gain the most information possible from animal models to support drug discovery and biomedical research. Our ACVP-certified pathologists provide research project support to pharmaceutical and start-up companies. With a focus on discovery and early state pre-clinical trials, our work spans the entire research process, beginning with planning, preparation of grants, implementation, through the evaluation of results.
Tufts full-service histology laboratory with complete molecular pathology capabilities, including routine and special stains, light and fluorescence immunohistochemistry (IHC), and in situ hybridization (ISH). With specialized expertise in IHC, our technical team can validate new antibodies and targets as well as perform high-throughput assays for larger projects. To support drug discovery we can pellet cultured cell lines for molecular phenotyping, and perform detailed analyses of xenografts in mouse models, including proliferation and apoptosis kinetics, and biomarker characterization. In collaboration with the Comparative Pathology Core at Tufts Medical Center in Boston, we also can meet your electron microscopy needs, both TEM or SEM.
We work with scientists every step of the way, providing real time feedback on research projects and suggestions for improvement. Our reports have been used to support a wide array of successful Investigational New Drug (IND) applications submitted to the FDA. Because we focus on discovery and perform biomedical research ourselves, we bring a scientific depth and rigor that is not routinely found in larger contract research organizations (CRO’s). With dozens of satisfied clients, most of them early and mid-stage biopharmaceutical companies, we welcome the opportunity to provide references upon request.
Biopsy, Autopsy, Discovery Pathology Services
You can learn more about our pricing for Discovery Pathology services in support of your research efforts